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| 1850 | - | City of San Francisco incorporated. |
| 1912 | - | Titanic sinks at 2:20 AM. |
| 1922 | - | the famed Poodle Dog Restaurant closes. |
| 1923 | - | insulin becomes generally available for diabetics. |
| 1928 | - | Alioto\s on Fisherman\s Wharf is founded. |
| 1955 | - | Ray Kroc starts the McDonald\s chain of fast food restaurants. |
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